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 Core Investigators (2013-2017)


Yumiko Saga Lab HP
Division of Mammalian Development, National Institute of Genetics
"Establishment of sexually dimorphic epigenome via RNA-mediated regulation"

Takashi Shinohara Lab HP
Department of Molecular Genetics, Graduate School of Medicine, Kyoto University
"Regulation of epigenetic stability in germ line stem cells and its relationship with cancer development"

Shinichiro Chuma Lab HP
Institute for Frontier Medical Sciences, Kyoto University
"Genome and epigenome program for mitosis to meiosis transition of germline stem cells"

Kuniaki Saito Lab HP
Keio University School of Medicine
"Molecular mechanisms of small RNA-mediated epigenetic programming"

Toshinobu Nakamura Lab HP
Laboratory for epigenetic regulation, Nagahama Institute of Bio-Science and Technology
"Epigenome dynamics and regulation in preimplantation embryos"

Masahito Ikawa Lab HP
Research Institute for Microbial Diseases, Osaka University
"Elucidation of the mechanism of fertilization and its role during the epigenetic reprogramming"

Yuichi Tsukada Lab HP
Advanced Biological Information Research Division, INAMORI Frontier Research Center, Kyushu University
"Regulation of epigenome in early mammalian embryos"

Atsuo Ogura Lab HP
BioResource Center, RIKEN
Takashi Kohda Lab HP
Department of Epigenetics, Medical Research Institute, Tokyo Medical and Dental University
"Analysis of epigenome dynamics in germ cells by nuclear transfer "

Hiroyuki Sasaki Lab HP
Division of Epigenomics and Development, Medical Institute of Bioregulation, Kyushu University
"Dynamics and regulation of genomic imprinting and DNA methylation"

 Advisory Board (2013-2017)


Fumitoshi Ishino
Tokyo Medical and Dental University

Mitinori Saitou
Kyoto University

Takashi Nagasawa
Osaka University

Norio Nakatsuji
Kyoto University

Toru Nakano
Osaka University

Ryuzo Yanagimachi
University of Hawaii


 Investigators (2014-2015) 

Hitomi Suzuki Lab HP
Department of Experimental Animal Model for Human Disease, Tokyo Medial and Dental University
"The regulation of primordial follicle pool via epigenetic modification"

Makoto Tachibana Lab HP
Institute for Enzyme Research, The University of Tokushima
"Regulation of germ cell function by H3K9 demethylation"

Satomi Kuramochi-Miyagawa Lab HP
Department Pathology, Medical School, Osaka University
"Application of artificial piRNA production system to epigenome engineering"

Akihiko Okuda Lab HP
Division of Developmental Biology, Research Center for Genomic Medicine, Saitama Medical University
"Molecular Mechanism of Induction of Spermatogenesis Program by Max Expression Ablation in Embryonic Stem Cells"

Soichiro Yamanaka Lab HP
Keio University School of Medicine
"Developing a new system to analyze the molecular basis of male epigenome formation in mouse GS cell"

Yoshiyuki Seki Lab HP
Department of Bioscience, School of Science and Technology, Kwansei Gakuin University
"Epigenetic reprogramming in primordial germ cells"

Kuniya Abe Lab HP
Mammalian Genome Dynamics, RIKEN BioResource Center
"Analyses of Epigenome formation processes at developmental flex points and comparative epigenomics of human-mouse primordial germ cells"

Hiroaki Okae Lab HP
Department of Informative Genetics, Environment and Genome Research Center, Tohoku University Graduate School of Medicine
"Dynamic regulation of DNA methylation during early human development"

Keiji Tanimoto Lab HP
Faculty of Life and Environmental Sciences, University of Tsukuba
"Epigenome dynamics at the mouse imprinting control region"

Yasushi Hirota Lab HP
Department of Obstetrics & Gynecology, Graduate School of Medicine, The University of Tokyo
"Epigenetic regulation of embryo implantation through embryo-uterine interactions"

Fugaku Aoki Lab HP
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo
"The role of maternal mRNA in the regulation of genome reprogramming after fertilization"

Mitsuhiro Endoh Lab HP
Research Institute for Radiation Biology and Medicine, Hiroshima University
"Epigenetic regulation of meiosis-related genes by MBLR-PRC1, an atypical PRC1-family Polycomb complex"

Hiroki Nagase Lab HP
Division of Cancer Genetics, Chiba Cancer Center Research Institute
"Development of DNA binding molecules to modify epigenetic state at specific genomic regions"

 Investigators (2016-2017)


Hirotsugu Ishizu Lab HP
Department of Biological Sciences, Graduate School of Science, The University of Tokyo
"Translational regulation by primary piRNA pathway"

Kazuki Kurimoto Lab HP
Department of Anatomy and Cell Biology, Graduate School of Medicine, Kyoto University
"Analysis of the regulatory mechanisms by the core pluripotency factors during epigenome reprogramming in germ cells"

Makoto Tachibana Lab HP
The Institute for Advanced Enzyme Research, The University of Tokushima
"Regulation of germ cell function by H3K9 demethylation"

Akihiko Okuda Lab HP
Division of Developmental Biology, Research Center for Genomic Medicine, Saitama Medical University
"Role of MAX as a negative regulator of meiosis and its underlying molecular mechanisms"

Keiichiro Ishiguro Lab HP
Department of Chromosome Biology, Institute of Molecular Embryology and Genetics, Kumamoto University
"Regulation of epigenome in meiotic cell cycle of germ cells"

Yoshiyuki Seki Lab HP
Department of Biomedical Chemistry, School of Science and Technology, Kwansei Gakuin University
"Molecular mechanism and artificial regulation of epigenetic reprogramming in primordial germ cells"

Toshie Shinagawa Lab HP
Laboratory of Molecular Genetics, RIKEN
"Molecular mechanisms of histone replacement in germ cells"

Kuniya Abe Lab HP
Mammalian Genome Dynamics, RIKEN BioResource Center
"Epigenomic regulations at developmental transition points and human-mouse comparative epigenomics"

Fugaku Aoki Lab HP
Department of Integrated Biosciences, Graduate School of Frontier Sciences, University of Tokyo
"The role of maternal mRNA in the regulation of genome reprogramming after fertilization"

Shinpei Yamaguchi Lab HP
Graduate school of Frontier Biosciences, Osaka University
"Heterochromatin dynamics in mouse primordial germ cell development"

Kei Miyamoto Lab HP
Graduate School of Biology-Oriented Science and Technology, Kinki University
"Molecular mechanisms of how somatic cell nuclei acquire totipotency "

Tomoya Kitajima Lab HP
Center for Developmental Biology, RIKEN
"Functional significance of large cytoplasmic size of oocytes"

Akihito Harada Lab HP
Research Center for Transomics Medicine, Institute of Bioregulation, Kyushu University
"Genome-wide analysis of histone variants in germ cell"

Contact

Head investigator:
Prof. Takashi Shinohara

Department of Molecular Genetics, Graduate School of Medicine, Kyoto University.

Yoshida-Konoe-cho,Sakyo-ku, Kyoto 606-8501, Japan

Secretariat:
Prof. Masahito Ikawa

Animal Resource Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University.

Yamadaoka 3-1, Suita, Osaka 565-0871, Japan

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